Objective: To optimize the shaping technology of the Genhuang Dispersible Tables and study the release characteristics in vitro. Method: The orthogonal design was used to obtain the optimal formulation with the disintegration of tablets;dissolution method and RP-HPLC method were used to study the release curve in vitro. Result: The proportion of each adjuvant in the optimal formulation consisted of 40% MCC as bulking agent

15% PVPP and 7% L-HPC as disintegrant.The prepared dispersible tables could be totally disintegrated within three minutes and crossed No.2 sieve

which subjected to the Chinese pharmacopoeia.The percentage of dissolution was more than 99%. Conclusion: The dispersible tables were in accordance with the standard.The process was operable

repeatable and suitable to the batch manufacture.