Objective: To observate the effect of Qili Qiangxin capsule on cardiac function and levels of brain natriuretic peptide in patients with chronic systolic heart failure(CHF). Method: One hundred patients with different causes of CHF were randomly divided into 2 groups

control group 48 patients were treated with conventional anti-failure therapy

such as salt restriction

rest

under the conditions used diuretics

angiotensin converting enzyme inhibitors

β receptor blockers

spironolactone

nitrates

etc.

if necessary

apply conditions digitalis

dobutamine inotropic drugs such as antibiotics.Qili Qiangxin group of 52 cases were treated by Qili Qiangxin capsule on the basis of control group

four pills once

three times a day.Treatment for 6 months.Clinical and left ventricular end diastolic diameter (LVEDD)

left ventricular ejection fraction (LVEF)

6 min walking distance

the serum B-type natriuretic peptide (BNP) and other in two groups were observed before and after treatment. Result: After 6 months

the total effective rate of Qili Qiangxin group was significantly higher than that of the control group (P<0.05).LVEDD and BNP of Qili Qiangxin group were significantly decreased more than before treatment and that of the control group (P<0.01 and P<0.05).LVEF

6 min walk distance of Qili Qiangxin group were significantly increased more than before treatment and that of the control group (P<0.01 and P<0.05).The side effects were not found in both groups. Conclusion: CHF patients in the conventional therapy were added Qili Qiangxin capsule

increased LVEF

improvement of left ventricular function

exercise tolerance

decrease plasma BNP levels

and good security.