Objective: To summarize the recent development on the utilization of enzyme engineering technology in obtaining active ingredients from traditional Chinese medicines. Method : The published articles on extracting active ingredients from traditional Chinese medicines by enzyme engineering technology were reviewed and analyzed. Result : The enzymatic lysis of cell wall for the extraction of substances

the directional extraction of active substances

and the enzymatic transformation of substances with low or no activity to highly active substances have been carried out with various traditional Chinese medicines

indicating that the enzymatic method is economically efficient and convenient in the production of highly active substances from traditional Chinese medicines. Conclusion :This study will provide a reference for the further research and development of enzymatic extraction and transformation of active substances from traditional Chinese medicines.