ObJective: To study the effects of removing blood stasis and anti-inflammatory of Dieda Xiaotong Tablet to provide an experimental foundation for clinical application. Method: The removing blood stasis effect was demonstrated with rat and guinea pig models of hemostasis induced by local punching and clamping accordingly. The anti-inflammatory effect was determined with the models of the swelling ear in mice and cotton ball induced granuloma in rat. The treatment (ig) of Dieda Xiaotong Tablet lasted for 7 days. Result :Dieda Xiaotong Tablet markedly reduced blue stain area of skin and Evans content of in hemostasis rats. It could also suppress ear swelling caused by dimethylbenzene in mice and cotton ball induced granuloma in rat (P<0.01). Conclusion: Dieda Xiaotong Tablet possesses obvious effect of removing blood stasis and anti-inflammatoion.