To investigate the technological parameters of the enrichment process of total flavones from Hypericum perforatum. with macroreticular resins. The static capacity absorption and the static rate of desorption of six types macroreticular resins were studied and compared respectively in o rder to find the optimum macroreticular resin. The technical process for purification of total flavones with the optimum macroreticular resin was screened by total flavones product. The results indicated that the absorption capacity and elution ratio of HPD-600 type of macroporous resin were the best in these types of macroporous resin.The optimum extraction condition was the concentrationan and the flow velocity of the original solution were 3.81 g·L-1 and 1 BV·h-1. The eluant was 70％ ethanol and the eluting velocity was 3 BV·h-1

The consumption of eluant was 3 BV.