Objective: To observe influences of the modified Banxia Baizhu Tianma Tang on experimental hyperlipidemia in rats. Method: Rats were given high fat diet for 4 weeks

resulting in model of hyperlipidemia

meanwhile the modified Banxia Baizhu Tianma Tang was given in three doses. During the drug administration

body weight

and the levels of TG

CHOL

LDL

HDL

apoA1

apoB

SOD

MDA were measured. Result: Compared with the model group

body weight in the rats of the high-dose group increased significantly. In the three drug dosage groups

serum triglyceride was significantly reduced.In the high-dose group

the serum CHOL and LDL levels were significantly reduced

compared with the model group (P <0.05). The serum HDL levels in the drug groups were elevated to some degree

but compared with the model group there was no significance. No significant difference in levels of serum apo A1 was found. The drug groups and the positive control of Xuezhikang lowered apo B levels

the high dose group showed the most obvious effect compared with the model group. The drug groups increased SOD activity

reduced MDA content to various degrees

among them the effect of high doses was most obvious. Conclusion: The modified Banxia Baizhu Tianma Tang shows clear improvement for hyperlipidemia-related indicators.