Objective: To discuss the therapeutic effects of application of Zicao ointment with partial clousure and ice compress in the treatment of the effusion of chemotherapy drugs. Method: To observe the injury situation of local tissue recovery

control group patients with effusion of chemotherapy drugs were cared with partial clousure and ice compress intermittently after 24 hours;therapy group patients added application of Zicao onitment based on the control group. Result : The overall efficient rate of therapy group 32 patients was 100%

and control group 20 patients was 90%。There was significant difference between these two groups (P<0.05). Conlusion: It is efficient to prevent the effusive tissue injury with western and Traditional Chinese Medicine method

and is better than single western method.