Objective: To observe and compare the effects of Chaihu Shugan San

Sijunzi Tang and Chaishu Sijun Tang on the apperant syndrome of Liver-gi stagnation and Spleen-qi deficiency (GYPX) in rat. Method : Rats were randomly divided into normal control group

GYPX group

Chaihu Shugan San group

Sijunzi Tang group and Chaishu Sijun Tang group

10 rats in each group. The animals except the controls were experienced by chronic restraint stress+excess fatigue+improper diet to form the model. The model rats were astricted for 3 hours in every morning

swimed for 10 minutes in water(22±1) ℃ and fed every other day

for 28d;normal control group without any stimulation and with natural feeding. On the 15th day

medicated group rats were given Chaishu Sijunzi Tang 4.27 g ·kg-1

Chaihu Shugan San 4.2 g ·kg-1

Sijunzi Tang 4.53 g ·kg-1

1 time/d accordingly; model group and normal group were given distilled water for 14 days. All the changes in behavior

body weight and temperature were observed and recorded. Result: Compared with normal group

the model rats shown the abnormal changes of behavior and the decrease of their weight and body temperature. Compared with model group

the behavior of the three medicated groups had improvement to some degrees. Chaihu Shugan San group’s rats increased the level of activity

emotional state of stability; Sijunzi Tang group’s rats improved markedly on the skin-fur appearance

appetite and the state of stool; Chaishu Sijun Tang rats had all respects such as the skin-fur

the level of activity

emotional reaction

sleep or appetite improved clearly. The three treatment groups’body weight and temperature all increased

of which Chaishu Sijun Tang group’s difference was obvious(P<0.05).There were significant differences among the three treatment groups in the increased body temperature(P<0.01).Compared with Chaihu Shugan San group

there was difference of the increased temperature(P<0.05)in Chaishu Sijun Tang group. Conclusion : Chaishu Sijun Tang had better effect on the model rats’apperant GYPX syndrome. There were some relativities among the three prescriptions

of which Chaishu Sijun Tang had the markest relativity with GYPX syndrome.