Objective: To evaluate the effect of the polysaccharide from Eclipta prostrasta L. on the immune function of mice. Method: Kunming mice were randomly divided into 5 groups

the low

middle

high doses of the polysaccharide

the positive drug group and normal control group

treated ig for 14 days. All the mice were experimented with peritoneal macrophage

hemolysin and hemolytic antibody plaques formation. Result: Compared with normal

polysaccharide of Eclipta prostrasta L. of three doses significantly increased the peritoneal macrophages phagocytic index and percentage(P<0.01)

significantly promoted the hemolysin and hemolytic plaque formation in normal mice

particularly at the low dosage. Conclusion: The polysaccharide of Eclipta prostrasta L. can significantly increase the immune function in normal mice.