Objective: To investigate the anti\|aging effect of Yishou Yin through experimental studies. Method: The subacute aging models were establishe by subcutaneous injection of D-galactose daily for consecutive 45 d in mice. Mice of normal group

model group

positive drug group (Vitamine E 20 mg \5kg-1) and three different doses of Yishou Yin (1

2

3 g crude drug \5kg-1) were intragastric administrated for 45 d. The level of superoxide dismutase (SOD)

cholinesterase (CHE) in serum and monoamine oxidase (MAO) in brain were detected. Result: Compared with model group

three doses Yishou Yin and the positive drug improved the activities of SOD and CHE in serum remarkably( P ＜0.05

P ＜0.01)

and the contents of MAO in brain were decreased notably

too ( P ＜0.01). Conclusion: Yishou Yin shows a good anti\|aging action on the subacute aging model induced by D-galactose

and this may be related to the activity of SOD

CHE and MAO in the body.