ZHONG Ying-jie, LI Liang, XU Fu-liang. Studies on extraction process of cichoric acid in Echinacea purpurea[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(4): 1-4.
ZHONG Ying-jie, LI Liang, XU Fu-liang. Studies on extraction process of cichoric acid in Echinacea purpurea[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(4): 1-4.DOI:
Objective: To establish the optimal extraction technology and to determine the quantity of cichoric acid from Echinacea purpurea. Method: Nine experiments were carried out through L9(34) orthogonal design. The contents of cichoric acid were determined by HPLC. Result: The best extraction condition obtained was 12 times amount 60% alcohol and extracted for 3 times
1.5 hours each time. Cichoric acid was linear within the range of 0.011~1.100 mg
r =0.999 8. The average recovery is 99.51%(RSD=1.01%
n=6). Conclusion : This optimal technology is stable and workable
can be used in industrial production. The determination method is suitable for quality control.