理气调补汤对运动性疲劳大鼠下丘脑-垂体-肾上腺轴的影响

王丛笑; 方素萍; 马丽华; 周军

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理气调补汤对运动性疲劳大鼠下丘脑-垂体-肾上腺轴的影响

更新时间：2024-09-23

- 理气调补汤对运动性疲劳大鼠下丘脑-垂体-肾上腺轴的影响
- Effect of Liqi Tiaobu Tang on Hypothalamic-Pituitary-Adrenal Axis in Fatigue Induced by Exercise in Rat
- 中国实验方剂学杂志 2010年16卷第5期页码：139-141
- 作者机构：
- 作者简介：
- 基金信息：
  
  北京市教育委员会人才强教项目资助课题(PXM2008-014206-053361)
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  中图分类号：
- 纸质出版日期：2010
- 稿件说明：
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王丛笑, 方素萍, 马丽华, 等. 理气调补汤对运动性疲劳大鼠下丘脑-垂体-肾上腺轴的影响[J]. 中国实验方剂学杂志, 2010,16(5):139-141.

WANG Cong-xiao, FANG Su-ping, MA Li-hua, et al. Effect of Liqi Tiaobu Tang on Hypothalamic-Pituitary-Adrenal Axis in Fatigue Induced by Exercise in Rat[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 139-141.
王丛笑, 方素萍, 马丽华, 等. 理气调补汤对运动性疲劳大鼠下丘脑-垂体-肾上腺轴的影响[J]. 中国实验方剂学杂志, 2010,16(5):139-141. DOI：

WANG Cong-xiao, FANG Su-ping, MA Li-hua, et al. Effect of Liqi Tiaobu Tang on Hypothalamic-Pituitary-Adrenal Axis in Fatigue Induced by Exercise in Rat[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 139-141. DOI：

摘要

目的: 探讨理气调补汤对运动性疲劳大鼠下丘脑-垂体-肾上腺轴的调节作用。方法: 30只健康雄性SD大鼠随机分为3组。采用大鼠游泳运动训练方式

观察大鼠最后1次力竭游泳的力竭时间、血清皮质酮、睾酮、血清和下丘脑β内啡肽含量等指标。结果: 理气调补汤可以延长大鼠游泳力竭的时间(P<0.01)

提高血清睾酮含量;降低血清β内啡肽含量。结论: 理气调补汤可以改善运动性疲劳大鼠下丘脑-垂体-肾上腺轴的功能

从而起到预防运动性疲劳的作用。

Abstract

Objective: To observe and to discuss the effect of Liqi Tiaobu Tang on hypothalamic-pituitary-adrenal axis in the rat of fatigue induced by exercise. Method: 30 male SD rats were randomly divided into 3 groups. Ⅰ and Ⅱ groups are all trained for 6 weeks with swimming. The last exhaustive swimming time

serum corticosterone

testosterone

and hypothalamic β-endorphin were observed. Result: Liqi Tiaobu Tang could extend the time for exhaustive swimming in rats(P<0.01)

increase the content of T

and decrease the content of serum β-endorphin. Conclusion: Liqi Tiaobu Tang improves hypothalamus-pituitary-adrenal axis function in the rat of fatigue induced by exercise. It may prevent the exercise fatigue.

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