Aim: To investigate the effects of Huachuanbaolie Granules(HCBL) on nonbacterial prostatitis and its anti-inflammatory and analgesia activity. Methods: Acute and chronic nonbacterial prostatitis model in rats were induced by carrageenin

Effects of HCBL on count of white blood cells

density of lecithin corpuscle in secretion and histological changes of prostates were observed. The anti-inflammatory activity was evaluated by xylene-induced ear edema in mice and cotton pellet-induced granuloma in rats. Analgesia activity was tested according to acetic acid-induced writhing in mice. Results: HCBL lowered the count of white blood cells

increased the density of lecithin corpuscle in secretion of prostates

and inhibited inflammatory infiltration

edema and fibroblast proliferation in carrageenin-induced acute or chronic prostatitic rats. Anti-inflammatory activity was confirmed in cotton pellet-induced granuloma in rat. HCBL could obviously decrease the writhing number induced by acetic acid and inhibit the ear edema induced by xylene in mice. Conclusion: The data suggest that HCBL has anti-inflammation and analgesia effects

It is an effective medicine for the treatment of prostatitis.