Objective: To study a environmental and effective separation of alkaloids in sophora flavescens ait. Technology. Method: With the adsorption and desorption of total alkaloids in S. flavescens ait. as parameters

screening a resin from the large-scale

and optimizing condition of absorption and desorption of alkaloids in S. flavescens ait. Result: The nonpolarity macroporous resin X-5 were selected out;The optimized condition of adsorption is that sample solution pH 10

saltion concentration is 1 mol·L-1

adsorption flow rate is 6 BV·h-1. The adsorption is 9.74 mg·mL-1; The optimized condition of desorption is that the alkaloids are desorpted by 60% ethanol (pH 1)

the desorption is 95.5%. Conclusions: Macroporous resin X-5 can directly and fast adsorpte alkaloids from S. flavescens ait. percolation fluid

and desorption of alkaloids is easy

does not pollute products and environment

it has great potential for development of green technology.