LIU Qi-hua, WEN Jin, SUN Yu-wen. Optimization of Extraction Technology of Bushen Yisui Granule by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(9): 8-11.
LIU Qi-hua, WEN Jin, SUN Yu-wen. Optimization of Extraction Technology of Bushen Yisui Granule by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(9): 8-11.DOI:
Objective: To optimize the extraction technology of Bushen Yisui Granule. Method: An orthogonal test was adopted in this study. The content of loganin
psoralen and isopsoralen was used as index for optimizing the extraction condition with ethanol for Cornus officinalis and Salvia miltiorrhiza. The content of icaiin and the dried decocting rates was used as index for optimizing the extraction condition with water. Result: The best ethanol extraction technology was to extract for 1 h with 8 times of 60% ethanol 3 times. The best water extraction technology was to extract for 1 h with 10 times of water 3 times. Conclusion: The optimized extraction technology was rational and can be used for the extraction process of Bushen Yisui Granule.