Objective: To observe and study Isotretinoin soft capsules (TaiErSi) combined with Qing-gan Qu-cuo recipe in treating cyst jialing river acne. Method: 50 patients cyst jialing river acne patients were randomly divided into two groups

Isotretinoin soft capsules (TaiErSi) 20mg

2 times every day. The treatment group (n=30) was added with qing-gan qu-cuo recipe daily.In the treatment of initial and 2

4

8 weeks

observing and studying the lesions recovery

assessing skin evaluation for 16 weeks and adverse reaction of recurrence. Result: The efficiency of treatment group and control group was 90.0% vs 45.0%. Total skin lesions means

inflammatory lesions means and noninflammatory lesions means of treatment group 8 weeks after treatment with before treatment

were statistically significant difference (P<0.05 or P<0.01). The control groups total skin lesions means and inflammatory skin lesions means of 8 weeks after treatment compared with before treatment were statistically significant differente (P<0.05 or P<0.01)

the noninflammatory lesions means of control group before and after treatment were no significant differente (P>0.05). 8 weeks after treatment

total skin lesions means and noninflammatory skin lesions means of treatment group are better than those of control group significantly(P<0.05 or P<0.01)

the inflammatory lesions means of both groups 8 weeks after treatment were no statistically significant difference between the two groups (P>0.05). Conclusion: Isotretinoin soft capsules combined with qing-gan qu-cuo recipe in treating Cyst jialing river acne has reliable effect

low recurrent rate and less adverse reactions.