Objective: To compare the effect of traditional Chinese medicine with western medicine therapy for chronic atrophic gastritis. Methods: Relevant literatures were reviewed via database and assessed via randomized controlled trial (RCT) scale.A1l reviewed literatures were assessed via Jadad quality scale. Data statistical analyses were performed by RevMan4.1 software. Results: Clinical efficient: since test for heterogeneity: P=0.31

it indicates the data have homogeneity

so we use the fixed effect model. OR=3.99

95%(2.98

5.33);Z=9.34

P<0.000 01. It means that Chinese medicine treatment for chronic atrophic gastritis symptom in improving clinical has obvious advantages compared with western medicine. For Pathologic biopsy and endoscopy

the test for heterogeneity: P=0.000 1

it indicates the data have heterogeneity

so we use the random-effect models OR=4.67

95%(3.64

5.99);Z=12.13

P<0.000 01. It means that Chinese medicine treatment for chronic atrophic gastritis symptom in improving laboratory medicine has obvious advantages compared with western medicine. Conclusion: TCM treatment for chronic atrophic gastritis shows curative effect

and there are obvious advantages compared with western medicine.