ZHAO Ping1, YE Zhi-wen1, HE Dan-xuan1, et al. Study on the Protective Effects of Jigucao Capsule in Rat Liver Fibrosis[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(10): 99-101.
ZHAO Ping1, YE Zhi-wen1, HE Dan-xuan1, et al. Study on the Protective Effects of Jigucao Capsule in Rat Liver Fibrosis[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(10): 99-101.DOI:
Objective:To research the influence of Jigucao Capsule to rat liver fibrosis
to provide a experimental basis for the expansion of clinical indications.Methods:Rat liver fibrosis model by 40% CCl4(v/v)subcutaneous injection was built up
and intervented with different concentrations of Jigucao Capsule suspensionorally.Results:Jigucao Capsule could improve the liver function of model rat
and increase serum TP
ALB.It could improve the rat serum antioxidant indicators
increase serum SOD content
and reduce the MDA content.It could reduce the pathological changes of the liver damage to show a lower value of liver fibrosis.Conclusion:Jigucao Capsule showed apparent protective effect to rat with liver fibrosis.It could significantly reduce the degree of liver fibrosis.