WU Zeng-li1, ZHAN Xue-kong1, MA Xiao-hua2, et al. Experimental Studies on Anti-inflammation,Analgesic Action for Ronggensheng Capsule[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(10): 92-93.
WU Zeng-li1, ZHAN Xue-kong1, MA Xiao-hua2, et al. Experimental Studies on Anti-inflammation,Analgesic Action for Ronggensheng Capsule[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(10): 92-93.DOI:
Objective:Observing the influence of Ronggensheng Capsule on anti-inflammation
analgesic action and detumescence in the adjuvant-induced arthritis rat.Methods:Rat adjuvant arthritis model was established by Freund's complete adjuvant to observe the joint inflammation and swelling;and hot plate and writhing method to observe the Ronggensheng Capsule's analgesic effect in rat.Results: Ronggensheng Capsule could inhibit the rat secondary ankle swelling of arthritis
reduce inflammation index;extend the latent period of licking hind foot in the hot-plate test in mice and significantly reduce the acetic acid-induced writhing number in mice(P<0.05 or P<0.01).Experiments confirmed that high-dose group and meloxicam had no significant difference.Conclusion:Ronggensheng Capsule has a good anti-inflammatory and analgesic effect on swelling.