YI Hong, GAO Jin, YANG Hua, et al. Several Varieties of Injections State with Surfactants's Quality Specification and Safety[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(1): 115-119.
YI Hong, GAO Jin, YANG Hua, et al. Several Varieties of Injections State with Surfactants's Quality Specification and Safety[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(1): 115-119.DOI:
This article is an attempt to compare six surfactants for injection
such as polysorbate 80
polyoxyethylene castor oil derivatives
poloxamer188
lecithin
Solutol HS 15
cyclodextrins
from various countries' standards of pharmacopoeias and respectively gives an overview of their chemical compositions
physical appearance
incompatibility of medicines and safety
which provides reference data for new drug research and clinical study of injections. As for the surfactants for injection that are not recorded in the chinese pharmacopoeia (2005)
we suggest that we introduce those foreign surfactants and make corresponding quality standards by referring to foreign standards.