HUANG Hua1, LIU Yan1, WANG Xin-jun2, et al. Experimental Investigations on the Action of L. Ointment for Treating Psoriasis[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(10): 78-80.
HUANG Hua1, LIU Yan1, WANG Xin-jun2, et al. Experimental Investigations on the Action of L. Ointment for Treating Psoriasis[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(10): 78-80.DOI:
Objective:To investigate the effect of Capparis spinosa L.Ointment on treatment for animal models' psoriasis
and to observe its anti-inflammative and itch-relieving actions.Methods: The percentage of the granular cells appeared on squamouis slices of mice tails was analyzed
the mitosis index of vaginal bottom cell in mitosis metaphase chromosome was counted
and times and duration of mice's itching caused by dextran were observed.Auricle swelling caused by xylene and phlogistic exudation of celiac capillary vessel in mice were measured.Results: Capparis spinosa L.Ointment possessed significant promoting effect on the formation of granular layer in mouse tail scale epidermis
showed significant inhibiting effect on mice vaginal epithelial mitosis
marked itch-relieving effect
alleviating effect on mice's auricle swelling induced by xylene and restraining effect on mice's celiac capillary vessel permeability.Conclusion: These results indicate that Capparis spinosa L.Ointment has effect on treatment for psoriasis in mouse models
and it also has effects of anti-inflammation and analgesia on the experiment mice.