YANG Li-xia1, DOU Wu-ying2, YAN Chun-lu3, et al. Study on Toxicity of Angelica Sinensis Injection and Astragalus Membranaceus Injection in Chorioallantoic Membrane Model[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(5): 46-48.
YANG Li-xia1, DOU Wu-ying2, YAN Chun-lu3, et al. Study on Toxicity of Angelica Sinensis Injection and Astragalus Membranaceus Injection in Chorioallantoic Membrane Model[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(5): 46-48.DOI:
Objective:To explore the toxicity of Angelica sinensis injection (ASI) and Astragalus membranaceus injection (AMI) in the chick embryo chorioallantoic membrane (CAM) model. Methods:Fertilized eggs were incubated for 7 days at 37.8℃
and randomly divided into 6 groups
and then were respectively treated with NS (negative control)
ASI
AMI
and different ratio of ASI and AMI.After another 3 days of incubation
the number of living chick embryos were counted. Results:The survival of chick embryos could not be inhibited by ASI and AMI
and our assay showed that no difference between therapy groups and negative control (P>0.05). Conclusion:ASI and AMI could be used to study angiogenesis by CAM.