Objective: To discuss the preparation

quality control and clinical efficacy of Huachangtongbian Tablets. Method : The TLC

HPLC were used for the identification and characterization of Chinese herbal medicines preparation and determination of chrysophanol respectively; The antitheses was used in the clinical observation. Result : The preparation technology is feasible. Clear spots were noted in the TLC of Cassia occidentalis and rhubarb; Chrysophanol was linear in the range of 0.016~0.24 μg( r= 0.999 7) with the maximum absorption at 413nm.The average recovery was 98.25% (RSD 1.40%

n=6); 125 cases with habitual constipation were used in clinical observation. The total effectiveness in the treatment group was 92.0%

significantly better than 76.0% in the control group. Conclusion : The preparation formula is reasonableand the technology is feasible.TLC and HPLC methods can be used in the quality control of the preparation

with which better clinical efficacy was observed and no adverse reactions occured.