LUO Duo-sheng, He Wei, GUO Jiao. Purification of Salvianolic Acid by Macroporous Resins[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 14-16.
LUO Duo-sheng, He Wei, GUO Jiao. Purification of Salvianolic Acid by Macroporous Resins[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 14-16.DOI:
Objective: To study the optimum conditions for the purification of salvianolic acid by macroporous resins. Method: The macroporous resin was selected and the purification process was evaluated by measuring the content of salvianolic acid B. Result: The HPD-300 maoroporous resin was the most effective one among the resins. The optimum conditions were screened
the adsorption capacity of HPD-300 macroporous resin was 172.4 mg/g
pH was 3.5; and the volume of 70% ethanol as eluent was 3 BV. By this method
the yield of salvianolic acid B was 88.11%; and the purity was 72.80%. Conclusion: The method is effective for purification of salvianolic acid.