三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响

李伟; 付萍; 陈颖丽; 杨铭; 王清

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三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响

更新时间：2024-01-04

- 三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响
- Effect of SanyangYisinkang Capsule on the Cardiohemodynamics and Myocardial Oxygen Consumption in Anesthetized Dogs
- 中国实验方剂学杂志 2008年14卷第12期页码：55-60
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- 基金信息：
  
  吉林省科技厅2002年科技发展重大项目(20020503-10)
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  中图分类号：
- 纸质出版日期：2008
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李伟, 付萍, 陈颖丽, 等. 三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响[J]. 中国实验方剂学杂志, 2008,14(12):55-60.

LI Wei, FU Ping, CHEN Ying-li, et al. Effect of SanyangYisinkang Capsule on the Cardiohemodynamics and Myocardial Oxygen Consumption in Anesthetized Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(12): 55-60.
李伟, 付萍, 陈颖丽, 等. 三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响[J]. 中国实验方剂学杂志, 2008,14(12):55-60. DOI：

LI Wei, FU Ping, CHEN Ying-li, et al. Effect of SanyangYisinkang Capsule on the Cardiohemodynamics and Myocardial Oxygen Consumption in Anesthetized Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(12): 55-60. DOI：

摘要

目的:观察三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响。方法:采用麻醉犬在体心脏实验法

经十二指肠给予三羊益心康胶囊

于给药后不同时间点测定血流动力学和心肌耗氧量各项参数。结果:三羊益心康胶囊能明显增加麻醉犬冠脉血流量、心输出量、心搏出量、心脏指数、心搏指数

降低总外周阻力和冠状动脉阻力

减少心肌耗氧量、心肌耗氧指数及心肌氧摄取率。结论:三羊益心康胶囊能明显改善麻醉犬血流动力学

降低心肌耗氧量。

Abstract

Objective:To study the effect of Sanyang Yisinkang Capsule on the cardiohemodynamics and myocardial oxygen consumption in anesthetized dogs.Methods: Expermental technology of in vivo heart of anestheticzed dogs was adopted.After Sanyang Yisinkang Capsule was administrated to the anestheticzed dogs through duodenum

the parameters of hemodynamice and oxygen consumption were determined at different times Results:The coronary flow

cardiac output

stroke volume

cardiac index

stroke index were increased

total peripheral resistance

resistance arteria coranaria were degraded and oxygen consumption of myocardium

oxygen consumption index

the cardiac muscle uptake rate were decreased.Conclusion:Sanyang Yisinkang Capsule can improve the cardiohemodynamics and myocardial oxygen consumption in anesthetized dogs.

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