Objective:To observe the clinical curative effect of icterus due to chronic cholestasis treated withpurgation dispersion purification harmonization.Methods: We analyzed etiology and pathogenesis of icterus due to chronic cholestasis and treating it under the guidance of Yin-yang

Zang-fu theory and molecular biological methods.We treated icterus due to chronic cholestasis with purgation dispersion purification harmonization

that is nourishing yin and fluid

circulating blood

Purging damp

heat

phlegm

and bloodstasis

and harmonizing Zang-fu.Results: The therapeutic method of purgation dispersion purification harmonization could erase patients' symptoms and signs

normalize their liver function indexes

including total bilirubin AST and ALT in serum.Conclusion: It was effective of Using purgation dispersion purification harmonization to treat icterus due to chronic cholestasis and its complications.It could help to clean up remnant icterus and lessen complications.