Objective:To observe the anti-bacteria and anti-inflammatory effects of Qufeng Zhiyang(QFZY)Tincture.Methods: The in vitro anti-bacteria and the experimentation of skin infected by pathogenic bacteria were established to appraise the bacteriostatic effect of QFZY Tincture.The mice ear edema caused by xylene and rat's hind paw swelling inflammatory model caused by carrageenan were employed to study the anti-inflammatory effects.Results: QFZY Tincture had strong inhibiting effect on staphylococcus aureus

bacillus coli

pseudomonas aeruginosa

staphylococcus coat

bacillus distortion

candida albicans.It could alleviate symptom of skin infection elicited by staphylococcus aureus or pseudomonas aeruginosa.QFZY Tincture could significantly suppress ear swell induced by xylene in mice

hind paw tumefaction in rat and decrease PGE2 in inflammatory tissue.Conclusion:QFZY Tincture had preferably anti-bacteria and anti-inflammatory effects.