Objective:The main Pharmacological effects of Xinshenhua Granule were investigated.Methods:The drugs were given by mouth.The negative control group and the positive control group were saline solution and shenghuatang pill respectively.The influences of the weights of uterus of mice induced by estrogen

writhing test induced by acetic acid and the function of mononuclear cells of mice were observed at three different doses of Xinshenhua granule.Results:The high dose and middle dose of Xinshenhua granule can markedly inhibit the weights of uterus of sex mature mice induced by diethylstilbestrol(P<0.01)

and can raised the phagocytic function of mice mononuclear cell(P<0.01).The high dose of Xinshenhua granule canmarkedly inhibit the number of writhing reaction compared with normal saline group(P<0.05).Conclusion:Xinshehua granule can inhibit the weights of uterus induced by diethylstilbestrol

has analgetic effect and can raise the immunity function.