Objective:To investigate the effect of anti-implanted tumour of Xiaoliu Tang in mice.Methods:To make a mode of implanted tumor with injecting HepG2 cells in the axilla of mice.The inhibitory effect on tumor was observed for the mice after Xiaoliu Tang was given orally.The inhibitory effect in HepG2 by Xiaoliu Tang with the method of MTT was investigated.Telomerase activity of HepG2 cells was observed with the method of PCR

ELISA.Results:The tumor in the administration groups was smaller than that of the controls

especially for in the big-dosage group(the inhibitatory rate is 41.88%).The results of MTT showed that the inhibitory rate of HepG2 cells was in dose dependent fashion.The high-dosage treatment group have significant inhibitory effect on telomerase activity of hepatocarcinoma.Conclusions:Xiaoliu Tang can inhibit hepatocarcinoma;its mechanism may correlate to inhibiting telomerase activity.