ZENG Ming1, ZHENG Shui-qing2, TAO Kai-zhong3, et al. Effect of Kudzu Extract on Kidney Function of Rats with Diabetes[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(8): 42-44.
ZENG Ming1, ZHENG Shui-qing2, TAO Kai-zhong3, et al. Effect of Kudzu Extract on Kidney Function of Rats with Diabetes[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(8): 42-44.DOI:
Objective:To observe the effects of Kudzu extract on kidney function in rats with diabetic nephropathy(DN)
and to probe its mechanism.Methods:The rat model of diabetic nephropathy was induced by streptozotocin.The effects of TFP on diabetic rats were detected by blood sugar before meal
the concentration of fructosamine
urea nitrogen
creatinine in blood serum
and levels of ET
6-keto-PGF1 in plasma
compared with aminoguanidin treatment.Results:The Kudzu extract could decrease the level of blood sugar
the concentrations of fructosamine
urea nitrogen
creatinine in blood serum
and levels of ET
6-keto-PGF1 in plasma
comparing to that of the diabetic model group(P<0.01
or P<0.05)remarkably.Conclusion:The Kudzu extract has preventive and therapeutic effects on DN.