GE Hong-yan1, YANG Jin-gang2, FANG Xue-xun2, et al. Inhibitory in vitro Activity of Caulis Polygoni Multiflori on Matrix Metalloproteinase[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(8): 29-31.
GE Hong-yan1, YANG Jin-gang2, FANG Xue-xun2, et al. Inhibitory in vitro Activity of Caulis Polygoni Multiflori on Matrix Metalloproteinase[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(8): 29-31.DOI:
Objective:To observe the inhibition of matrix metalloproteinase(MMP) by Caulis Polygoni Multiflori.Methods:Decreased the degrade rate of substrate is associated with the inhibition of MMP.We studied the inhibitory activity of Caulis Polygoni Multiflori on MMP by observing the degrade rate of substrate.Results:Caulis Polygoni Multiflori inhibited the MMP-16 activity
and the IC50 was 21 μg/mL.Conclusion: The Caulis Polygoni Multiflori has the inhibitory activity of MMP-16.