ZHANG Ruo-nan1, 3, WANG San-hu2, et al. An Experimental Study on the Anti-tumor Effects of Duhuojisheng Decoction in Tumor Bearing Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(10): 28-31.
ZHANG Ruo-nan1, 3, WANG San-hu2, et al. An Experimental Study on the Anti-tumor Effects of Duhuojisheng Decoction in Tumor Bearing Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(10): 28-31.DOI:
Objective:To study the anti-tumor effects of Duhuojisheng Decoction on mice bearing sarcoma 180 and its possible mechanism.Methods:S180 bearing mice as model
effects of Duhuojisheng Decoction on tumor weight and the pathological diagnosis of tumor tissue were investigated.Modified MTT assay was used to determine immunological function in bearing mice.Results:Duhuojisheng Decoction could markedly inhibit the tumor weight of S180
the rate of inhibition ranged from 32.45~43.75 percent.Duhuojisheng Decoction could prompt tumor tissue large area necrosis and inflammation cell infiltration
activate proliferating ability of T cells
markedly increase activity of natural killers(NK) and secretion of interleukin-2(IL-2).Conclusion:Duhuojisheng Decoction had anti-tumor effects by regulating immune system.