REN Jian-xun, LIN Cheng-ren, Wang Min, et al. The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 34-36.
REN Jian-xun, LIN Cheng-ren, Wang Min, et al. The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 34-36.DOI:
Objective:To study the effect and mechanism of Niuhuang Jiangya Capsule on the function of platelet in rats.Methods:Healthy SD rats were fed with Niuhuang Jiangya Capsule(0.3
0.15
0.075 g·kg-1)for 7days;then the platelet adhension rates and the ADP-induced platelet agglutinate rate as well as the contents of CaM and TXA2 in platelets were measured.Results:Niuhuang Jiangya Capsule could reduce the platelet adhension rate and the ADP-induced platelete agglutinate rate
as well as the contents of CaM and TXA2 in platelets.Conculsion:Niuhuang Jiangya Capsule can suppress platelet agglutinate and adhension by interventing different pathways of platelet activation.