Objective:To investigate the effect of Jiuganqing capsule on alcoholic fatty liver.Methods:Alcoholic fatty liver of Wister rat was in duced by ig 56° alcohol liquid 5 mL·kg-1 twice a day for 4 week.The model is determined by histopathologic examination.The model group was given alcohol liquid as mentioned above.The masculine drug group was given Gypenosides ig 25 mg·kg-1 daily and alcohol as the model.Jiuganqing capsule high

middle and low dose-group was separately give ig 0.6

0.3

0.15 g·kg-1 and alcohol as the modes for 4 week.The content of ALT

AST

TG

T-CHO

SOD

MDA

TP

Alb and TNF-a in serum were detected.The hepatic index was calculated by weighing liver.The activity of TG

TC

MDA

ALT

AST and SOD in hepatic hemogenate were detected.Results:Jiuganqing capsule can obviously reduce activity of ALT

AST and the content of T-CHO、TG、MDA

TNF-α but increase the content of Alb and activity of SOD.Conclusion:Jiuganqing capsule has obviously therapeutic effect on alcoholic fatty liver in rat.