配伍对黄芩汤中甘草酸溶出率的影响

陈建真; 吕圭源; 罗小敏; 叶磊

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配伍对黄芩汤中甘草酸溶出率的影响

更新时间：2024-01-04

- 配伍对黄芩汤中甘草酸溶出率的影响
- Influence of Compatibility on Glycyrrhezic acid in Huangqin Decoction
- 中国实验方剂学杂志 2008年14卷第5期页码：35-37
- 作者机构：
- 作者简介：
- 基金信息：
  
  浙江省教育厅课题(20030953)
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- 纸质出版日期：2008
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陈建真, 吕圭源, 罗小敏, 等. 配伍对黄芩汤中甘草酸溶出率的影响[J]. 中国实验方剂学杂志, 2008,14(5):35-37.

CHEN Jian-zhen, LV Gui-yuan, LUO Xiao-min, et al. Influence of Compatibility on Glycyrrhezic acid in Huangqin Decoction[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(5): 35-37.
陈建真, 吕圭源, 罗小敏, 等. 配伍对黄芩汤中甘草酸溶出率的影响[J]. 中国实验方剂学杂志, 2008,14(5):35-37. DOI：

CHEN Jian-zhen, LV Gui-yuan, LUO Xiao-min, et al. Influence of Compatibility on Glycyrrhezic acid in Huangqin Decoction[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(5): 35-37. DOI：

摘要

目的:建立黄芩汤各配伍煎液中甘草酸的HPLC含量测定方法

研究配伍对甘草酸含量的影响。方法:采用L8(27)正交设计法

以HPLC法测定各配伍样品中甘草酸含量。结果:黄芩、白芍和大枣对甘草酸的含量影响差异不显著

两两交互作用不显著。结论:黄芩、白芍、大枣对甘草酸含量无显著影响。

Abstract

Objective:To develop a quantitative method for determination of glycyrrhezic acid in decoctions prepared from various combinations of the recipe named Huangqin Decoction and to investigate the content changes of glycyrrhezic acid in different decoctions.Methods: Eight decoctions of Radix Et Rhizome Glycyrrhizae either alone or in combination with one or more of the other three components were prepared.The contents of glycyrrhezic acid in the eight decoctions were determined by RP-HPLC.Results: For Radix Scutellariae

Radix Paeoniae Alba and Fructus Jujubae

The difference of glycyrrhezic acid contents is insignificant statistically in 8 decoctions.Conclusion: Effect of other 3 herbal components on the contents of glycyrrhezic acid is not obvious.

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