艾可清胶囊对高效抗病毒逆转录疗法的增效减毒作用

马伯艳1; 符林春1; 蔡卫平2; 陈谐捷2; 胡英杰1; 谭行华2

您当前的位置：

首页 >

文章列表页 >

艾可清胶囊对高效抗病毒逆转录疗法的增效减毒作用

更新时间：2024-09-23

- 艾可清胶囊对高效抗病毒逆转录疗法的增效减毒作用
- Clinical Effect Analysis of Aikeqing Capsule Combined with HAART on Cure for HIV/AIDS
- 中国实验方剂学杂志 2007年13卷第8期页码：60-63
- 作者机构：
- 作者简介：
- 基金信息：
  
  教育部科学技术研究重点项目(02109);广东省科技计划资助项目(2003C33904);广东省中医药管理局资助项目(203105);广州市卫生局科研重点项目资助(2004);广州中医药大学博士后科技基金资助项目(2005)
- DOI：
  中图分类号：
- 纸质出版日期：2007
- 稿件说明：
移动端阅览
马伯艳1, 符林春1, 蔡卫平2, 等. 艾可清胶囊对高效抗病毒逆转录疗法的增效减毒作用[J]. 中国实验方剂学杂志, 2007,13(8):60-63.

MA Bo-yan1, FU Lin-chun1, CAI Wei-ping2, et al. Clinical Effect Analysis of Aikeqing Capsule Combined with HAART on Cure for HIV/AIDS[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(8): 60-63.
马伯艳1, 符林春1, 蔡卫平2, 等. 艾可清胶囊对高效抗病毒逆转录疗法的增效减毒作用[J]. 中国实验方剂学杂志, 2007,13(8):60-63. DOI：

MA Bo-yan1, FU Lin-chun1, CAI Wei-ping2, et al. Clinical Effect Analysis of Aikeqing Capsule Combined with HAART on Cure for HIV/AIDS[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(8): 60-63. DOI：

摘要

目的:通过对7例接受高效抗病毒逆转录疗法(HAART)的人类免疫缺陷病毒/艾滋病(HIV/AIDS)患者加用艾可清胶囊进行治疗的临床观察

考察中药复方制剂艾可清胶囊辅助HAART治疗增效减毒作用。方法:7例HIV/AIDS患者在进行HAART治疗的同时加用中药艾可清胶囊

分别在治疗前、治疗后3个月和治疗后6个月记录症状体征积分(积分1)、症状舌脉积分(积分2)、体重

生存质量(卡洛夫斯基积分

Karnovsky Score)

并检测HIV RNA定量、T淋巴细胞亚群、血常规、谷丙转氨酶(ALT)、谷草转氨酶(AST)。结果:治疗6个月后

患者HIV复制得到有效控制;CD4、CD8、CD4/CD8在加用艾可清胶囊后3个月及6个月均较疗前升高

其中CD4细胞计数与CD4/CD8在治疗6个月时与治疗前比较分别为P<0.01、P<0.05;CD4/CD8疗后6个月与疗后3个月相比P<0.05。患者的积分1、积分2明显下降(P<0.05)、血常规及肝功能有改善的趋势。结论:艾可清胶曩显示出与实验室研究结果相符的对HAART疗法增效减毒的作用。

Abstract

Objective:To study the effectiveness of Aikeqing Capsule to attenuate adverse effect and enhance curative effect of HAART by the clinical observation of 7 HIV/AIDS patients who have been taken HAART.Methods:7 HIV/AIDS patients on HAART treatment took Aikeqing Capsules orally.These patients were given plasma HIV viral load test

CD4

CD8 cell count

blood test and liver function test and their symptoms and signs were evaluated by the established evaluation criteria including scores of symptoms and signs(Score 1)

scores of symptoms and tongue and pulse examination(Score 2).Body weight and the quality of life were valuated by Karnovsky Score before and after the treatment of three months and six months.Results:After the treatment of 6 months

the copy of HIV of the patients were controlled effectively.CD4 and CD8 counts and CD4/CD8 increased after the treatment of three months or six months

and CD4 counts and CD4/CD8 were signficantly higher than before treatment(P<0.01

P<0.05).Score 1 and Score 2 significantly decreased

The abnormal indexes of the blood test and live function were also improved after the treatment.Conclusion:Aikeqing Capsule can attenuate adverse effects and enhance curative effects of HAART.It agrees with the results achieved from the animal experiments.

关键词

Keywords

references

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

艾可清胶囊对高效抗病毒逆转录疗法的增效减毒作用