WEN Fu-chun1, XU Jia-jie2, WANG Yu-hong3, et al. Effect of Anshenbunao Syrup on Learning and Memory Capability and Contents of Monoamine Neurotransmitter Inside Brain in Juvenile Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 46-48.
WEN Fu-chun1, XU Jia-jie2, WANG Yu-hong3, et al. Effect of Anshenbunao Syrup on Learning and Memory Capability and Contents of Monoamine Neurotransmitter Inside Brain in Juvenile Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 46-48.DOI:
Objective:To study the effect of Anshenbunao Syrup on learning and memory capability and the contents of monoamine neurotransmitters inside brain in juvenile mice.Methods:The learning and memory capability of juvenile mice was investigated by Y-water maze test.The contents of monoamine neurotransmitters were investigated by fluorescence.Results:Anshenbunao Syrup had memory-enhancing effects on juvenile mice.In addition
Anshenbunao Syrup could significantly increase the contents of 5-hydroxytryptamine(5-HT)、dopamine(DA) and norepinephrine(NE) inside mice'brain
but it had no influence on the content of 5-hydroxyindole acetic acid(5HIAA).Conclusion:Anshenbunao Syrup could improve the learning and memory capability of juvenile mice
and its mechanism may be related to the increase of 5-HT