精制藿胆方及拆方抗炎药理作用研究

冼彦芳1; 索娟1; 黄晓丹2; 侯少贞1; 陈建南1; 叶木荣1; 苏子仁1

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精制藿胆方及拆方抗炎药理作用研究

更新时间：2024-01-04

- 精制藿胆方及拆方抗炎药理作用研究
- A Pharmacological Study on Anti-inflammatory Effects of Refined Huodan Recipe
- 中国实验方剂学杂志 2007年13卷第4期页码：54-56
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- 纸质出版日期：2007
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冼彦芳1, 索娟1, 黄晓丹2, 等. 精制藿胆方及拆方抗炎药理作用研究[J]. 中国实验方剂学杂志, 2007,13(4):54-56.

XIAN Yan-fang1, SUO Juan1, HUANG Xiao-dan2, et al. A Pharmacological Study on Anti-inflammatory Effects of Refined Huodan Recipe[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(4): 54-56.
冼彦芳1, 索娟1, 黄晓丹2, 等. 精制藿胆方及拆方抗炎药理作用研究[J]. 中国实验方剂学杂志, 2007,13(4):54-56. DOI：

XIAN Yan-fang1, SUO Juan1, HUANG Xiao-dan2, et al. A Pharmacological Study on Anti-inflammatory Effects of Refined Huodan Recipe[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(4): 54-56. DOI：

摘要

目的:研究精制藿胆方及其拆方抗炎药理作用。方法:采用角叉菜胶所致大鼠足趾肿胀、二甲苯所致小鼠耳廓肿胀、醋酸所致小鼠腹腔毛细血管通透性增高以及大鼠棉球肉芽肿的方法

探讨抗炎作用。结果:精制藿胆方及其拆方均对大鼠角叉菜胶足趾肿胀、二甲苯所致小鼠耳廓肿胀、醋酸所致小鼠腹腔毛细血管通透性增高以及大鼠棉球肉芽肿的炎症模型有明显的抑制作用。广藿香油、猪胆粉两药配伍存在极显著的交互作用。结论:精制藿胆方具有显著的抗炎作用。方药配伍呈协同增效关系。

Abstract

Objective:To study the anti-inflammatory effects of refined Huodan recipe and its disassembled prescriptions.Methods:The animal models of rat's toes swelling induced by carrageenan

mouse's auricle swelling induced by xylene

the increase of capillary permeability in mice induced by acetic acid

the rat granuloma induced by cotton ball were used to determine the anti-inflammatory effects of refined Huodan recipe and its disassembled prescriptions.Results:Refined Huodan recipe and its disassembled prescriptions have obvious inhibitory action on rat's toes swelling induced by carrageenan

on mouse's auricle swelling induced by xylene

on the increase of capillary permeability in mice induced by acetic acid

and on rat granuloma induced by the cotton ball.Oleum pogostemonis and Pulvis fellis suis have remarkable interaction.Conclusions:Refined Huodan recipe and its disassembled prescriptions have remarkable anti-inflammatory effects.The recipe shows synergistic action and compatibility in composition.

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