WANG Jin-ping, ZENG Ming, BIAN Jia-ming, et al. The Effect of Gegen Compound on Monoamines of Posttraumatic Stress Disorder in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 48-50.
WANG Jin-ping, ZENG Ming, BIAN Jia-ming, et al. The Effect of Gegen Compound on Monoamines of Posttraumatic Stress Disorder in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 48-50.DOI:
Aim:Observing the changes of monoamines neurotransmitter in posttraumatic stress disorder of rat and the influence of Gegen compound.Methods:The model of posttraumtaic stress disorder of rat was used.HPLC-ECD techniques were used to analyze the levels of DA、5-HT、AD、NE.Results:The levels of DA
5-HT in plasma and hypothalamus of posttraumaic stress disorder in rats decreased significantly while the levels of plasma NE、AD increased.Gegen compound can increase the levels of DA
5-HT in plasma and hypothalamus and decrease the levels of NE、AD in plasma.Conclusion:Gegen compound can enhance the antistress ability of posttraumatic stress disorder in rats.