CHEN Xue-gong1, ZHOU Xue-mei1, ZHANG Qiong-yu2, et al. The Effect of DongMeiYin on Advanced Glycation end Products in the Renal Cortex of Early Diabetic Nephropathy Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(1): 41-43.
CHEN Xue-gong1, ZHOU Xue-mei1, ZHANG Qiong-yu2, et al. The Effect of DongMeiYin on Advanced Glycation end Products in the Renal Cortex of Early Diabetic Nephropathy Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(1): 41-43.DOI:
Objective:To evaluate the effects of DongMeiYin(DMY) on advanced glycation end products(AGEs) in the diabetic rats
and investigate the mechanism of preventing and treating early diabetic nephropathy(DN).Methods:The rat early DN model was induced by injection of streptozotocin(STZ).The changes of the blood glucose
uA1b
uα1-MG and AGEs in the renal cortex and the effects of DMY were observed.Results:The blood glucose
uA1b
uα1-MG and AGEs of the model rats were obviously increased.DMY could decrease the parameters effectively.Conclusion:DMY could inhibits the AGEs and reduce the ua1b