WANG Wen-lai, ZHAO Hong-xia, BAI Wei-guo. Optimization of Extract Technology of Cortex Phellodendri in Qinggong Xiaoyan Suppository[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(11): 4-5.
WANG Wen-lai, ZHAO Hong-xia, BAI Wei-guo. Optimization of Extract Technology of Cortex Phellodendri in Qinggong Xiaoyan Suppository[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(11): 4-5.DOI:
Objective:To optimize the optimal alcoholic reflux and extrcact technology of Cortex Phellodendri in the Qinggong Xiaoyan Suppository by the orthogonal test.Methods:Using the orthogonal design
to optimize the reflux alcohol concentration
alcohol amount and extract times of Cortex Phellodendri in the Qinggong Xiaoyan Suppository with the content of berberine hydrochloride and the rate of creaming as the index.Results:Adding 5 times amount of 70% alcohol
refluxing and extracting for 1.5 hour(totally extracting for 3 times)Conclusion:The reflux alcohol concentration and extract times are the main factor to influence the extraction of berberine hydrochloride in Cortex Phellodendri.This technology is a simple method and suitable for industrial production.