Objective:To investigate the antitussive and expectorant effects of Succus bambusaes.Methods:Cough models were conducted by 17.5% citric acid-induced in guinea pig and 28% ammonia-induced in mouse to observe the antitussive efect of succus bambusae.Tracheal phenol red test in mouse and the in vitro tracheal mucociliary transport activity of rabbit trachea slice were used to investigate their expectorant effects.Results:Succus bambusaes of 50 mL·kg-1、25 mL·kg-1 could prolong the incubation period of cough and reduce the frequency of cough citric acid-induced in guinea pig(P<0.001)

and Succus bambusaes of 20 mL·kg-1 could prolong the incubation period of cough and reduce the frequency of cough ammonia-induced in mouse(P<0.05)

and succus bambusaes of 20 mL·kg-1、10 mL·kg-1 could obviously increase the tracheal excretion of phenol red(P<0.05) and speed up the tracheal mucociliary transport(P<0.05)

compared with that of the control group.Conclusion:Succus bambusaes has antitussive and expectorant effects.