CAO Kang, CHEN Guang-liang, LI Li. Effect of Yinxing-Danshen Granule on Myocardial Ischemic Injury Induced by Isoprenaline[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(4): 51-53.
CAO Kang, CHEN Guang-liang, LI Li. Effect of Yinxing-Danshen Granule on Myocardial Ischemic Injury Induced by Isoprenaline[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(4): 51-53.DOI:
Objective:To observe the effect of Yinxing-Danshen Granule on myocardial ischemic injury induced by isoprenaline in rats.Methods:Rat myocardial ischemia was induced by subcutaneous injection of isoprenaline(8 mg/kg).The descent of J point at different time after injecting isoprenaline were examined
and the serum creatine kinase(CK)
lactate dehydrogenase(LDH)
superoxide dismutase(SOD)and malondial dehyde(MDA)were detected.Result:Yinxing-Danshen Granule(35 g/kg、10.5 g/kg) can obviously inhibit descent of J point in rat myocardial ischemia induced by isoprenaline
enhance serum SOD activity
and inhibit the activities of serum CK、LDH、and MDA.Conclusion:Yinxing-Danshen Granule may obviously ameliorate myocardial ischemic injury induced by isoprenaline in rat.