Objective:To observe the influence of Jin Gu Tablet(JGT) on the development and rehabilitation of osteoarthritis(OA).Methods:The knee joint was fixed with the piaster bandage to make the model of rabbit OA

JGT was orall given for 4 weeks.After brake was applied for 6 weeks

the brake was removed 2 weeks later

measurement of indexes was carried out.Results:JGT can Obviously improve rabbit OA's scope of activity of knee joint

Compared with the model group

the middle

high dosage's Ca/P ratio obviously rises

every dosage group of JGT can inhitit swelling of thickness of slippery membrane of joint

alleviate the inflammation symptom of OA and obviously improve the pathology changing of slippery membrane and cartilage.The middle

high dosage can also obviously strengthen the activation of SOD of slippery membrane.Conclusion:JGT can lighten returning becoming of joint cartilage

obviously inhitit the slippery membrane's inflammation and improve SOD activity.The reoults Showed that JGT has effects on OA.