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纸质出版日期:2006
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郑国燊, 余尚贞, 石青, 等. 冰黄五苓散喷雾干燥工艺研究[J]. 中国实验方剂学杂志, 2006,12(9):1-2.
ZHANG Guo-shen, YU Shang-zhen, SHI Qing, et al. Study on Process for the Spray Drying of BINGHUANGWULING Pulveres[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(9): 1-2.
目的:选择冰黄五苓散喷雾干燥的最佳工艺条件。方法:应用正交试验法
以每小时药粉产量、含水量为考察指标
对影响冰黄五苓散喷雾干燥过程的塔前风温、风压和浸膏相对密度等三因素进行考察。结果:正交试验法设计的三个因素中
考察收粉量
浸膏的相对密度影响较显著
入塔风压和塔前风温影响不显著;考察含水量
浸膏的相对密度、入塔风压和塔前风温的影响均不显著。结论:最佳工艺条件为入塔风温180℃
入塔风压-1500Pa
浸膏相对密度为1.22;采用喷雾干燥工艺生产的冰黄五苓散有效成分中大黄素的含量和水浸出物明显高于原冰黄五苓液。
Objective: To selects the optimum conditions for the spraydrying of BINGHUANGWULING Pulveres. Methods: The process was studieds by orthogonal experimental design with the average output of the extract powder and water percent as the detective marker about the relative density of the extractive
the blast pressure and the wind temperature. Results: The relative density of the extractive is table effect and the other conditions are notable effect. Conclusion: It's the optimum process:The wind temperature is 180℃
The blast pressure is-1500Pa
The relative demsity is 1.22;the content of emodin in the BINGHUANGWULING Pulveres manufactured by the process of the spaydrying was higher than the BINGHUANGWULING Mixture.
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