ZHANG Xiao-huan1, HU Jian-ping2, LI Ying1. Study on Separated Recipes of Dark Plum Pill in Treating Diabetes[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(9): 41-43.
ZHANG Xiao-huan1, HU Jian-ping2, LI Ying1. Study on Separated Recipes of Dark Plum Pill in Treating Diabetes[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(9): 41-43.DOI:
Subject:Based on the theory of treating polydipsia in diabetes through adjusting liver's function
choose Dark plum pill(DPP)as the basic recipe of treating polydipsia in diabetes
and study the effect and mechanism in experiment.Method:Take SD rats and set up hyperglycemia models induced by alloxan.Then rats were randomly divided into seven groups:DPP group
pathology group
sour flavour(SF)group
bitter flavour(BF)group
sweet flavour(SF)group
pungent flavour(PF)group and Xiaoke Wan(XKW) group
and take another 12 normal rats as normal group.After two weeks of treatment
rats were examined via routine methods for the measurements of the fasting blood sugar
insulin
triglyceride
cholesterol
and to take the pathological examination of the pancreas.Result:Among separated recipes groups
the BF group's BS decreased most evidently
and so did the PF group in blood lipid.But on the comprehensive effect of BS
blood lipid and general state
DPP group was better than other groups evidently.Conclusion:DPP can decrease blood sugar
blood lipid and ameliorate general state.The possible mechanism is as follows:DPP may facilitate the regeneration of pancreatic island β-cell and the restore of β-cell function
stimulate excretion of the β-cell
increase the sugar utilization of peripheral tissue and increase the number of glycogen in liver.