SUN Wei-feng, LUO Ping, XU Wei, et al. Effects of Xiezhuo Chubi Decoction on Serum Uric Acid Level in Model of Hyperuricemic Mice[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(9): 36-37.
SUN Wei-feng, LUO Ping, XU Wei, et al. Effects of Xiezhuo Chubi Decoction on Serum Uric Acid Level in Model of Hyperuricemic Mice[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(9): 36-37.DOI:
Aim:The purpose is to study hypouricemic effect of xiezhuo chubi decoction on serum uric acid level in hyperuricemic mice.Methods:Hypoxanthine
the pre-substance of uric acid
was used to create mouse model with hypeuricemia
and to observe the effect of xiezhuo chubi decoction.Results:When xiezhuo chubi decoction and allopurinol take orally
the serum uric acid level of the hypoxanthine-pretreated mice was marked decrease
and was able to elicitdose-dependent hypouricemic effects.Conclusion:Xiezhuo chubi decoction was shown to possess potent hypouricemic effects in hyperuricemic mice pretreated with hypoxanthine.