Objective:Collected the data about the toll-like receptors(TLRs) to provide the studying ideas and methods for the anti-inflammatory herb drugs.Sources of the data:Mainly collected the achievements of TLR in the late 10 years.Choice of the data:Reviwed TLR'S discovery

distribution and structural feature

especially their effector cell ligad

signal transduction pathway and functions

aggregately analyzed TLR's current research situations.Results:Nowadays' study mainly concentrated on the signal transduction way

but the drug's mechanism study on it are insufficient.Conclusion:The further research of TLRs will provide scienti ic evidence for prevention and treatment of diseases

at the same time

these may provide new methods to the study of new drugs' effective targets.