LI Jian-rong, WU Lan-sheng, ZHANG Guang-ping. The Relation Between Immune Function and the Model of Hysteromyoma in Rat[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(7): 24-27.
LI Jian-rong, WU Lan-sheng, ZHANG Guang-ping. The Relation Between Immune Function and the Model of Hysteromyoma in Rat[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(7): 24-27.DOI:
Objective:The relation between immune function and the model of hysteromyoma of rat were studied.Method:Rats were injected with diethyl 1 stilbestrol
and progesterone and diethyl stilbestrol together.The immune organs were observed
levels of CD3
CD4 and CD4/CD8 in serum were measured by flow cytometer;estrogen receptor was analyzed by radioligand combination assay.Result:Compared with normal group
the weight of thymus
the levels of CD3
CD4 and CD4/CD8 of model group injected with diethyl stilbestrol and progesterone was significantly increased.Conclusion:It is suggested that the low immunologic functions in model rats with estrogen and progesterone together was lower
might be related to the levels of estrogen receptor.