CHENG Long, LIANG Ri-xin, YANG Bin, et al. Experimental Study on Regulation of Lipid Metabolism and Antioxidation by Extract of Carthamus Tinctorius L. in Hyperlipidemia Rat[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(9): 25-27.
CHENG Long, LIANG Ri-xin, YANG Bin, et al. Experimental Study on Regulation of Lipid Metabolism and Antioxidation by Extract of Carthamus Tinctorius L. in Hyperlipidemia Rat[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(9): 25-27.DOI:
Objective:To observe the effects of extract from Carthamus tinctorius L on regulation of lipid metabolism
hemorheological indexes
antioxidation in rat with hyperlipidemia.Methods:Using hyperlipidemia animal model replicated by hyperlipidemia forage
TC
TG
HDL
LDL
hemorheological indexes
levels of MDA
SOD
NO were assayed.Results:The levels of TG
TC
LDL-C in all groups treated with the water extract of Carthamus tinctorius L. were significantly reduced. The alcohol extract of Carthamus tinctorius L.showed a decreased action for TC and increased one for SOD activity; For the two extracts
the decreased plasma viscosity and content of MDA were found.Conclusions:The extract of Carthamus tinctorius L. regulated the lipid metabolism
improved hemorheological indexes
increased the activity of scavenging free radicals in rat with hyperlipidemia.